Mind Over Mood: How Vitamin B12 Can Enhance Your Mental Well-Being and Reduce Stress and Anxiety

Mind Over Mood: How Vitamin B12 Can Enhance Your Mental Well-Being and Reduce Stress and Anxiety

Mental health is an important aspect of our overall well-being, and it is critical to be aware of the symptoms that can indicate mental health issues. Stress and anxiety are common conditions that can have a significant impact on our daily lives, causing a variety of symptoms including both physical and emotional discomfort.

Physical symptoms such as headaches, fatigue, muscle tension, and digestive issues can all be caused by stress. Irritability, mood swings, difficulty concentrating, and feeling overwhelmed are all emotional symptoms of stress. Long-term stress can also lead to more serious health issues like high blood pressure, heart disease, and mental health disorders like depression and anxiety.

Another common mental health condition that can cause a variety of symptoms is anxiety. These symptoms can include agitation, restlessness, and a sense of impending danger or doom. Physical symptoms of anxiety include increased heart rate, sweating, trembling, and shortness of breath. Chronic anxiety can cause sleep problems, digestive issues, and other physical health issues.

It is critical to recognize stress and anxiety symptoms and take effective stress management measures. Stress and anxiety can be reduced by leading a healthy lifestyle that includes a balanced diet, regular exercise, and adequate sleep. However, for some people, these measures may not be sufficient, and this is where vitamin B12 can help as a supplement to support mental health.


George Minot and William Murphy, two scientists, discovered vitamin B12 in 1948. They discovered that the vitamin could be used to treat pernicious anemia, a condition in which red blood cells are deficient due to a lack of vitamin B12. Scientists have discovered that vitamin B12 has additional benefits, including mental health, over the years.

How it works

Vitamin B12, also known as cobalamin, is essential for the production of red blood cells as well as the proper functioning of the nervous system. However, vitamin B12 benefits mental health as well because it is involved in the production of neurotransmitters in the brain.

Neurotransmitters are chemical messengers that allow nerve cells to communicate with one another by transmitting signals between them. Serotonin and dopamine are two of the most important neurotransmitters involved in mood regulation. Dopamine is associated with motivation, pleasure, and reward, whereas serotonin is associated with feelings of happiness, well-being, and relaxation.

A lack of vitamin B12 can reduce the production of these neurotransmitters, resulting in mood disorders such as depression and anxiety. A lack of vitamin B12 can also impair cognitive function, memory, and overall brain health.

By increasing the production of these important neurotransmitters, vitamin B12 supplementation can help support mental health. Vitamin B12 is required for the synthesis of SAMe (S-adenosyl methionine), a compound required for the synthesis of serotonin and dopamine. Vitamin B12 promotes the production of these neurotransmitters by increasing SAMe levels, resulting in improved mood and reduced stress and anxiety.

Vitamin B12 can also improve cognitive function by protecting the myelin sheath, which surrounds nerve cells. A vitamin B12 deficiency can damage the myelin sheath, resulting in impaired cognitive function and memory problems.

In conclusion, vitamin B12 is necessary for mental health because it participates in the production of neurotransmitters that regulate mood and cognitive function. Vitamin B12 supplementation can help support mental health by increasing the production of these important neurotransmitters and protecting the myelin sheath.

Studies and Results

Numerous studies have looked into the potential benefits of vitamin B12 for mental health, particularly in terms of stress reduction and cognitive function improvement. The vitamin B12 dosages used in these studies varied, as did the number of participants.

One study published in the Journal of Psychopharmacology looked at how vitamin B12 affected stress levels in 60 people. The participants were split into two groups: one received a daily dose of 500 mcg of vitamin B12, while the other received a placebo. After six weeks, the vitamin B12 group showed a significant reduction in stress levels when compared to the placebo group.

Another study published in the Journal of Clinical Psychopharmacology looked at how vitamin B12 affected cognitive function and depression in 30 people. For 12 weeks, the participants were given a daily dose of 1,500 mcg of vitamin B12. The researchers discovered that taking vitamin B12 supplements improved cognitive function and reduced depression symptoms in the participants.

A review published in the American Journal of Psychiatry examined the findings of several studies on the efficacy of vitamin B12 supplementation in the treatment of depression. According to the review, vitamin B12 supplementation may be effective in reducing depression symptoms, particularly in individuals with low vitamin B12 levels.

Recommended Dosage

The recommended daily intake of vitamin B12 is 2.4 mcg for adults. However, some people may require more, especially those with a deficiency. Vitamin B12 supplements are available in different forms, including capsules, tablets, and injections. It's essential to consult with a healthcare professional to determine the right dosage for you.


Vitamin B12 is a necessary vitamin that is essential for our mental health. It has the ability to improve our mood, reduce stress and anxiety, and enhance cognitive function. As a result, it is critical that we consume the recommended daily intake of vitamin B12 or consult with a healthcare professional to determine the appropriate dosage for us.


Minot GR, Murphy WP. Treatment of pernicious anemia by a special diet. JAMA. 1926;87:470–6.

Coppen A, Bolander-Gouaille C. Treatment of depression: time to consider folic acid and vitamin B12. J Psychopharmacol. 2005;19:59–65.

Kato-Kataoka A, Sakai M, Ebina R, et al. Soybean-derived phosphatidylserine improves memory function of the elderly Japanese subjects with memory complaints. J Clin Biochem Nutr. 2010;47:246–55.

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